NSUN2 polyclonal antibody
产品名称: NSUN2 polyclonal antibody
英文名称: NSUN2 polyclonal antibody
产品编号: PAB23182
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against recombinant NSUN2.
- Immunogen:
- Recombinant protein corresponding to amino acids of human NSUN2.
- Sequence:
- PFVFIPEDDPLFPPIEKFYALDPSFPRMNLLTRTTEGKKRQLYMVSKELRNVLLNNSEKMKVINTGIKVWCRNNSGEEFDCAFRLAQ
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Isotype:
- IgG
- Storage Buffer:
- In PBS, pH 7.5 (40% glycerol, 0.02% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Immunohistochemistry (1:500-1:1000)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Entrez GeneID:
- 54888
- Protein Accession#:
- Q08J23
- Gene Name:
- NSUN2
- Gene Alias:
- FLJ20303,MISU,SAKI,TRM4
- Gene Description:
- NOL1/NOP2/Sun domain family, member 2
- Omim ID:
- 610916
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Maturation of cytoplasmic tRNAs includes splicing of introns, which are located 1 nucleotide 3-prime from the anticodon in all intron-containing tRNA genes. In tRNA-leu(CAA), the first position of the anticodon, C34, is converted to 5-methylcytosine, a modification necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. NSUN2 encodes a methyltransferase that catalyzes the intron-dependent formation of 5-methylcytosine at C34 of tRNA-leu(CAA) (Brzezicha et al., 2006 [PubMed 17071714]).[supplied by OMIM
- Other Designations:
- 5-methycytoisine methyltransferase,Myc-induced SUN-domain-containing protein,NOL1/NOP2/Sun domain family 2,NOL1/NOP2/Sun domain family 2 protein,tRNA methyltransferase 4 homolog