CCND3 monoclonal antibody, clone 6H4
产品名称： CCND3 monoclonal antibody, clone 6H4
英文名称： CCND3 monoclonal antibody, clone 6H4
产品编号： MAB10522
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant CCND3.
- Immunogen:
- Recombinant protein corresponding to human CCND3.
- Host:
- Mouse
- Theoretical MW (kDa):
- 32
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Isotype:
- IgG1
- Storage Buffer:
- In ascites (0.03% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:10000)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Entrez GeneID:
- 896
- Gene Name:
- CCND3
- Gene Alias:
- -
- Gene Description:
- cyclin D3
- Omim ID:
- 123834
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- D3-type cyclin,G1/S-specific cyclin D3,OTTHUMP00000016390
- Interactome
- Related Disease
- Adenocarcinoma
- Alzheimer Disease
- Alzheimer disease
- Breast cancer
- Breast Neoplasms
- Cerebral Amyloid Angiopathy
- Esophageal Neoplasms
- Genetic Predisposition to Disease
- Kidney Failure, Chronic
- Lung Neoplasms
- Neoplasm Invasiveness
- Neuroblastoma
- Ovarian cancer
- Ovarian Neoplasms
- Pulmonary Disease, Chronic Obstructive
- Urinary Bladder Neoplasms
- Werner syndrome