AFP (N-term) Peptide
产品名称： AFP (N-term) Peptide
英文名称： AFP (N-term) Peptide
产品编号： P0398
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of AFP.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human AFP.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein A purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:50-100)
Immunohistochemistry (1:10-50)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- EpCAM and alpha-fetoprotein expression defines novel prognostic subtypes of hepatocellular carcinoma.
Yamashita T, Forgues M, Wang W, Kim JW, Ye Q, Jia H, Budhu A, Zanetti KA, Chen Y, Qin LX, Tang ZY, Wang XW.Cancer Res. 2008 Mar 1;68(5):1451-61.
- 2.
- Single nucleotide polymorphism in the promoter region of human alpha-fetoprotein (AFP) gene and its significance in hepatocellular carcinoma (HCC).
Chen GG, Ho RL, Wong J, Lee KF, Lai PB.Eur J Surg Oncol. 2007 Sep;33(7):882-6. Epub 2007 Apr 12.
- 3.
- Mesenchymal hamartoma of the liver associated with features of Beckwith-Wiedemann syndrome and high serum alpha-fetoprotein levels.
Cajaiba MM, Sarita-Reyes C, Zambrano E, Reyes-Mugica M.Pediatr Dev Pathol. 2007 May-Jun;10(3):233-8.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of HepG2 cell lysate with AFP polyclonal antibody (Cat # PAB3074).
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma reacted with AFP polyclonal antibody (Cat # PAB3074) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Entrez GeneID:
- 174
- Protein Accession#:
- NP_001125;P02771
- Gene Name:
- AFP
- Gene Alias:
- FETA,HPAFP
- Gene Description:
- alpha-fetoprotein
- Omim ID:
- 104150
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq
- Other Designations:
- OTTHUMP00000160480,alpha-1-fetoprotein,alpha-fetoglobulin
- Related Disease