Anti-Smad2 Monoclonal Antibody-蛋白质/抗原/多肽-试剂-生物在线
北京索莱宝科技有限公司
Anti-Smad2  Monoclonal Antibody

Anti-Smad2 Monoclonal Antibody

商家询价

产品名称: Anti-Smad2 Monoclonal Antibody

英文名称: Anti-Smad2 Monoclonal Antibody

产品编号: K000096M

产品价格: 0

产品产地: 北京

品牌商标: Solarbio

更新时间: 2024-12-27T14:02:10

使用范围: null

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Anti-Smad2 Monoclonal Antibody

品牌:Solarbio | 货号:K000096M
商品货号:商品品牌:规格基本售价:选择规格
K000096M-50ulSolarbio50ul960.00元
K000096M-100ulSolarbio100ul1600.00元
英文名称Mouse Smad2 Monoclonal Antibody
应用2WB ICC
克隆类型2Monoclonal Antibody
别名Smad2
应用WB,ICC
稀释比例WB1:500 ICC1:100
交叉反应Human
蛋白分子量60kDa
Gene ID4087
保存Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment.
亚型IgG1
免疫原Purified recombinant human Smad2 protein fragments expressed in E.coli.
性状Lyophilized or Liquid
Swiss ProtQ15796
克隆号6H5-E3-C11
克隆类型Monoclonal Antibody
来源Mouse
背景资料The protein encoded by this gene belongs to the SMAD,a family of proteins similar to the gene products of the Drosophila gene mothers against decapentaplegic (Mad) and the C.elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways.This protein mediates the signal of the transforming growth factor (TGF)-beta,and thus regulates multiple cellular processes,such as cell proliferation,apoptosis,and differentiation.This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein.In response to TGF-beta signal,this protein is phosphorylated by the TGF-beta receptors.The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4.The association with SMAD4 is important for the translocation of this protein into the nucleus,where it binds to target promoters and forms a transcription repressor complex with other cofactors.This protein can also be phosphorylated by activin type 1 receptor kinase,and mediates the signal from the activin.Alternatively spliced transcript variants have been observed for this gene.[provided by RefSeq,May 2012]