ITGB4 monoclonal antibody, clone 450-9D
产品名称： ITGB4 monoclonal antibody, clone 450-9D
英文名称： ITGB4 monoclonal antibody, clone 450-9D
产品编号： MAB5239
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against native ITGB4.
- Immunogen:
- Native purified human ITGB4.
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- 450-9D recognizes the human beta4 integrin (also known as CD104), a 205kD glycoprotein which associates with the alpha6 integrin to form the alpha6/beta4 complex. CD104 is expressed on epithelial cells, Schwann cells and various tumour cell lines. 450-9D recognizes an extracellular epitope on the CD104 molecule.
- Form:
- Liquid
- Isotype:
- IgG1
- Storage Buffer:
- In PBS, pH 7.4 (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Flow Cytometry (10ul of the suggested working dilution (1:25-1:100) to label 106 cells in 100ul)
Immunohistochemistry (Frozen sections) (1:500-1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Application Image
- Western Blot
- Immunohistochemistry (Frozen sections)
- Immunoprecipitation
- Flow Cytometry
- Entrez GeneID:
- 3691
- Gene Name:
- ITGB4
- Gene Alias:
- CD104
- Gene Description:
- integrin, beta 4
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- CD104 antigen,GP150,integrin beta 4,integrin beta-4 subunit